2026

Activating p53Y220C with a mutant-specific small molecule

X. Zhu*, W.S. Byun*, D.E. Pienkowska, K.T. Nguyen, M. Wang, S.A. Nettles, S. Gourisankar, N.A. Phillips, J. Gerhartz, Q. Geng, T. Qiu, J. Zhong, Z. Jiang, R.C. Sarott, S.M. Hinshaw, T. Zhang, L.D. Attardi, R.P. Nowak, N.S. Gray. Nat. Commun. (2026).

2025

A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death

M.N. Nix*, S. Gourisankar*, R.C. Sarott, B.G. Dwyer, S.A. Nettles, M.M. Martinez, H. Abuzaid, H. Yang, Y. Wang, J.M. Simanauskaite, B.A. Romero, H.M. Jones, A. Krokhotin, T.N. Lowensohn, L. Chen, C. Low, M.M. Davis, D. Fernandez, T. Zhang, M.R. Green, S.M. Hinshaw, N.S. Gray, G.R. Crabtree.

Rewiring the fusion oncoprotein EWS/FLI in Ewing sarcoma with bivalent small molecules

M.J. Bond*, R.P. Golden*, G. DiGiovanni, B. Howard, R.C. Sarott, B.A. Karim, S. Gourisankar, G. Alexe, K. Ross, H.M. Jones, B.G. Dwyer, N.S. Gray, K. Stegmaier. J. Am. Chem. Soc. 147, 49, 44739–44758 (2025).

Synaptic activity causes minute-scale changes to BAF complex composition and function

S. Gourisankar*, S.A. Nettles*, W. Wenderski, J.A. Paulo, S.H. Kim, K.C. Roepke, C. Ellis, H.Z. Abuzaid, S.P. Gygi, G.R. Crabtree. Molecular Cell 85, 12, 2374-89 (2025).

2024

Re-localizing transcriptional kinases to activate apoptosis

R.C. Sarott*, S. Gourisankar*, B. Karim*, S.A. Nettles, H.Yang, B.G. Dwyer, J.M. Simauskaite, J. Tse, H. Abuzaid, A. Krokhotin, T. Zhang, S.M. Hinshaw, M.R. Green, G.R. Crabtree, N.S. Gray. Science, 386, eadl5361 (2024).

Context-specific functions of chromatin remodellers in development and disease

S. Gourisankar, A. Krokhotin, W. Wenderski, G.R. Crabtree. Nature Rev. Genetics, 25, 340-361 (2024).

2023

Rewiring cancer drivers to activate apoptosis

S. Gourisankar*, A. Krokhotin*, W. Ji*, X. Liu, C-Y. Chang, S. H. Kim, Z. Li, W. Wenderski, J.M. Simanauskaite, H.Yang, H. Vogel, T. Zhang, N.S. Gray, G.R. Crabtree. Nature, 620, 417-425 (2023).

2022

2021

ARID1B is a dosage-sensitive regulator of PRC distribution and Hox gene regulation in human neural progenitors

E.Y. Son*, A. Krokhotin*, S. Gourisankar, C-Y. Chang, G.R. Crabtree.

2020

Chemical inhibitors of a selective SWI/SNF function synergize with ATR inhibition in cancer cell killing

E.J. Chory, J.G. Kirkland, C-Y. Chang, V.D. D’Andrea, S. Gourisankar, E.C. Dykhuizen, G.R. Crabtree. ACS Chem. Biol., 15, 1685-1696 (2020).

Pre-2020

Formation of small gold nanoparticle chains with high NIR extinction through bridging with calcium ions

R.J. Stover*, E. Moaseri*, S. Gourisankar, N. Rahbar, B. Changalvaie, M. Iqbal, T. Truskett, K. Johnston. Langmuir, 32, 1127-1138 (2016).

Quenched assembly of NIR-active gold nanoclusters capped with strongly bound ligands by tuning particle charge via pH and salinity

R.J. Stover, A.K. Murthy, G.D. Nie, S. Gourisankar, B.J. Dear, T.M. Truskett, K.V. Sokolov, K.P. Johnston. J. Phys Chem C., 118, 14291-14298 (2014).

Equilibrium gold nanoclusters quenched with biodegradable polymers

A.K. Murthy, R.J. Stover, A.U. Borwankar, G.D. Nie, S. Gourisankar, T.M. Truskett, K.V. Sokolov, K.P. Johnston. ACS Nano., 7, 239-251 (2013).

Charged gold nanoparticles with essentially zero serum protein adsorption in undiluted fetal bovine serum

A.K. Murthy, R.J. Stover, W.G. Hardin, R. Schramm, G.D. Nie, S. Gourisankar, K.V. Sokolov, K.P. Johnston. J. Am. Chem. Soc., 135, 7799-7802 (2013).

Silver-free synthesis of nitrate-containing room-temperature ionic liquids

N.W. Smith, S.P. Gourisankar, J.L. Montchamp, S.V. Dzyuba. New J. Chem., 35, 909-914 (2011).